Heart India

: 2019  |  Volume : 7  |  Issue : 2  |  Page : 41--42

Preface to the second issue of Heart India 2019

Alok Kumar Singh 
 Department of Cardiology, Opal Hospital, Varanasi, Uttar Pradesh, India

Correspondence Address:
Dr. Alok Kumar Singh
Department of Cardiology, Opal Hospital, Varanasi, Uttar Pradesh

How to cite this article:
Singh AK. Preface to the second issue of Heart India 2019.Heart India 2019;7:41-42

How to cite this URL:
Singh AK. Preface to the second issue of Heart India 2019. Heart India [serial online] 2019 [cited 2020 Jul 15 ];7:41-42
Available from: http://www.heartindia.net/text.asp?2019/7/2/41/261834

Full Text

In this issue of “Heart India,” we are publishing seven original research articles and two case reports. As per the World Health Organization's report, about 40% of people aged >25 years had hypertension in 2008.[1] In the first original research article, Mahmood et al. have studied the prevalence and predictors of hypertension among adults of urban Lucknow, India. The prevalence of hypertension was 14.67% among urban adults. Hypertension was significantly higher among individuals aged >40 years and those who consumed tobacco products. A higher proportion of the hypertensives belonged to the illiterate category. There was a significant difference in hypertension prevalence in different education classes. Respondents living in overcrowded houses had higher odds of having hypertension than those not experiencing overcrowding.

B-type natriuretic peptide (BNP) is initially formed as a 134-amino acid precursor known as pre-pro-BNP and subsequently converted to the active 32-amino acid BNP which corresponds to the C-terminal sequence and a 76-amino acid N-terminal fragment, N-terminal prohormone BNP. Among them, BNP qualifies all criteria for an ideal biomarker.[2] In the second original research article, Saha et al. have studied the role of BNP level in predicting future cardiac events in patients presenting with dyspnea (a hospital-based study). The authors of this study have concluded that BNP at admission and BNP at discharge determine prognosis in patients presenting with dyspnea. The study shows BNP as a better predictor of prognosis than ejection fraction or past history of any cardiac event.

Cardiac disorders complicate approximately 1%–3% of pregnancies and present a real challenge to treating obstetricians and other health-care providers.[3] In the third original research article, Shuchi et al. have done a critical analysis of all pregnancies with heart disease, misses, and near misses over a 1-year period along with an expert group so as to optimize outcome and improve patient care – a needbased analysis. The authors of this study have shown that, out of 9563 deliveries, there were 108 cases of pregnancy with heart disease (1.12%). Majority of the patients in the study cohort belonged to low socioeconomic status and had rural background. Thirty-six patients (33.33%) were primigravida; majority presented for antenatal care in the third trimester. Eighty-two patients were (75.92%) in functional Class (New York Heart Association) I–II, predominant cardiac lesion was rheumatic valvular disease diagnosed in 101 patients (93.5%); 60 patients (58.82%) had vaginal delivery, 63 (64%) were delivered before 37 weeks and 6 patients had medical termination of pregnancy. Ten patients (9.2%) developed cardiac failure and eight (7.4%) had atrial fibrillation. The authors of this study have highlighted the need for training of physicians and obstetricians working at peripheral centers for early diagnosis, timely referral, and strengthening prepregnancy counseling.

In the fourth original research article, Badrinath et al. have studied the lipid parameters and their correlation with coronary artery disease in those patients who are already on statin therapy. The authors of this study have concluded that non high-density lipoprotein (HDL), total cholesterol/HDL, and low-density lipoprotein/HDL ratios were found to be useful in predicting the coronary artery disease attacks in future. In the fifth original research article, Iqbal et al. have studied the role of thiamine supplementation in the treatment of patients with heart failure. The authors of this study have concluded that thiamine supplementation significantly improved the clinical and echocardiographic parameters. Thiamine supplementation is cost-effective, is benign, and is easily available with significant clinical benefits.

In the sixth original research article, Chandra et al. have studied the determinants of coronary collateral formation in patients with acute ST-elevation myocardial infarction (STEMI) and total occlusion of infarctrelated artery. The authors of this study concluded that high-grade coronary collaterals were seen more commonly in patients who had angina prior to STEMI. Highgrade collaterals were significantly high in middleaged individuals compared to the elderly. Diabetes mellitus and smoking status were negative predictors of highgrade collaterals. In the seventh original research article, Mir et al. have studied the clinical profile, diagnosis, and outcome of congenital heart disease (CHD) in neonates. The authors of this study have concluded that neonates with CHD have a unique presentation, and they carry a poor outcome unless diagnosed early and managed appropriately. A high index of suspicion is very important as many neonates with CHD are asymptomatic initially.

In the first case report, Chawala et al. reported their observation of coronary steal in postcoronary artery bypass grafting (CABG) patients as a cause of angina in post-CABG patients of unique clinical significance. In the second case report, Singla et al. reported a rare case of bacterial endocarditis associated with ostium secundum atrial septal defect.


1World Health Organization. Global Brief on Hypertension. World Health Organization; 2013. Available from: http://apps.who.int/iris/bitstream/10665/79059/1/WHODCOWHO. [Last accessed on 2018 Oct 17].
2Boldanova T, Noveanu M, Breidthardt T, Potocki M, Reichlin T, Taegtmeyer A, et al. Impact of history of heart failure on diagnostic and prognostic value of BNP: Results from the B-type natriuretic peptide for acute shortness of breath evaluation (BASEL) study. Int J Cardiol 2010;142:265-72.
3Konar H, Chaudhuri S. Pregnancy complicated by maternal heart disease: A review of 281 women. J Obstet Gynaecol India 2012;62:301-6.