Year : 2019 | Volume
: 7 | Issue : 1 | Page : 26--30
Echocardiographic abnormalities in patients with cirrhosis and relation to disease severity
PG Anish, Narayanapillai Jayaprasad, Suresh Madhavan, Raju George
Department of Cardiology, Government Medical College, Kottayam, Kerala, India
Context: Cirrhosis is the leading cause for hepatic transplantation worldwide. Heart is one of the most adversely affected organs in cirrhosis and it increases morbidity and mortality in these patients.
Aims: The objective of this study is to identify the echocardiographic abnormalities in patients with cirrhosis and their relation to severity of cirrhosis.
Subjects and Methods: An observational study was done on patients with cirrhosis (n = 55) and age- and sex-matched controls (n = 30). Detailed echocardiographic examination including 2D, M-mode, pulsed-wave Doppler, tissue Doppler, and 2D speckle-tracking imaging was performed. Severity of cirrhosis was defined by model for end-stage liver disease (MELD) score. Comparison of various echo parameters among cases and controls and among the two groups with MELD score >12 and <12 was made.
Results: The major echocardiographic abnormalities noticed were left ventricular hypertrophy in 47.3%, diastolic dysfunction in 40%, pulmonary artery hypertension in 32.7%, and pericardial effusion in 3.6% of patients. Among the various echocardiographic parameters, mitral annular velocity, deceleration time, isovolumetric relaxation time (IVRT), Sm velocity, e' velocity, E/e' ratio, and average global longitudinal strain (GLS) were significantly different in cirrhosis patients compared to the control population. Mitral annular a velocity and IVRT were significantly more in cirrhotic patients with MELD score >12.
Conclusions: Cirrhosis is associated with increased LV mass and cardiac output. Diastolic dysfunction was present in 40% of patients. Although systolic function by ejection fraction was normal in cirrhotic patients, GLS was less compared to controls.
Dr. Narayanapillai Jayaprasad
Department of Cardiology, Government Medical College, Kottayam, Kerala
|How to cite this article:|
Anish P G, Jayaprasad N, Madhavan S, George R. Echocardiographic abnormalities in patients with cirrhosis and relation to disease severity.Heart India 2019;7:26-30
|How to cite this URL:|
Anish P G, Jayaprasad N, Madhavan S, George R. Echocardiographic abnormalities in patients with cirrhosis and relation to disease severity. Heart India [serial online] 2019 [cited 2019 Aug 26 ];7:26-30
Available from: http://www.heartindia.net/article.asp?issn=2321-449x;year=2019;volume=7;issue=1;spage=26;epage=30;aulast=Anish;type=0