Heart India

: 2019  |  Volume : 7  |  Issue : 1  |  Page : 1--2

Preface to the first issue of Heart India 2019

Alok Kumar Singh 
 Department of Cardiology, Opal Hospital, Varanasi, Uttar Pradesh, India

Correspondence Address:
Dr. Alok Kumar Singh
Department of Cardiology, Opal Hospital, Varanasi, Uttar Pradesh

How to cite this article:
Singh AK. Preface to the first issue of Heart India 2019.Heart India 2019;7:1-2

How to cite this URL:
Singh AK. Preface to the first issue of Heart India 2019. Heart India [serial online] 2019 [cited 2020 Feb 25 ];7:1-2
Available from: http://www.heartindia.net/text.asp?2019/7/1/1/255288

Full Text

In this issue of “Heart India,” we are publishing one editorial, one review article, four original research articles, one case report, and one journal scan article.

Aspirin is a widely used antiplatelet drug for the management of cardiovascular disease (CVD) for the last five decades. Multiple studies have established its role in the secondary prevention of CVD. The pivotal Antithrombotic Trialists Collaboration meta-analysis[1] demonstrated 12% reduction in serious vascular events with the use of aspirin which was driven principally by 23% reduction in nonfatal myocardial infarction. There was also a 14% reduction in ischemic strokes which was counterbalanced by increase in hemorrhagic strokes by 32%. In this issue, Dr. Pradhan discusses the role of aspirin in primary prevention in the background of recently published studies of aspirin.

Heart failure reversal therapy (HFRT) is a combination of Panchakarma and allied therapies used by Ayurveda physicians for chronic heart failure patients. This observational study by Sane et al. was done to evaluate HFRT in heart failure with reduced ejection fraction-affected postmenopausal females have shown encouraging results, but findings need to be replicated in randomized controlled clinical trial before being utilized in routine clinical practice. Spontaneous coronary artery dissection (SCAD) is defined as an epicardial coronary artery dissection that is not associated with atherosclerosis or trauma and not iatrogenic. Madhavan has analyzed his center's acute coronary syndrome patient's data and published his experience in the second original research article on this issue. Of 3708 patients studied, SCAD was seen in 5.9% patients with 78.8% females and was responsible for 31.4% and 6% of acute coronary syndrome (ACS) in females aged <50 and >50 years, respectively. The mean age of presentation was 47.2 years. Age <50 years, female sex, emotional and physical stress, and fibromuscular dysplasia (FMD) were the risk factors identified. In-hospital and 6-month mortality rate was 3.1% and 6.3%, respectively. 31.9% of SCAD patients were diagnosed to have FMD on follow-up. Only 4.1% of patients belonged to the peripartum period. Medical management is superior in hemodynamically stable SCAD patients as compared to invasive strategies.

Hypertension is a major contributing factor for all forms of CVD. Health-related quality of life (HRQoL) is important in hypertension management, given the chronic nature and lifelong self-management associated with the disease. In the third original research article, Naik et al. have studied the impact of hypertension on HRQoL. Cirrhosis is the leading cause for hepatic transplantation worldwide. Heart is one of the most adversely affected organs in cirrhosis and it increases morbidity and mortality in these patients. In the fourth original research article, Anish et al. have studied the echocardiographic abnormalities in patients with cirrhosis and their relation to the severity of cirrhosis. The major echocardiographic abnormalities reported in this study were left ventricular hypertrophy in 47.3%, diastolic dysfunction in 40%, pulmonary artery hypertension in 32.7%, and pericardial effusion in 3.6% of patients.

Coronary bifurcation lesions account for approximately 15%–20% of percutaneous coronary interventions.[2] Due to their association with procedural complications such as restenosis and adverse events, they are considered a subset of complex lesions. Although provisional stenting remains the default strategy in such cases, stent placement in the main branch may lead to side branch ostial stenosis, compromising side branch access. Sumit has reported a case of a bifurcated lesion in the left anterior descending artery diagonal, which was managed by implanting a single stent using the proximal optimizing technique (POT), side branch inflation, and final POT (POT-side-POT technique), without final kissing balloon. In the last, in journal scan article, twenty four landmark studies which have been published in 2018 have been summarized.


1Antithrombotic Trialists' (ATT) Collaboration, Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, et al. Aspirin in the primary and secondary prevention of vascular disease: Collaborative meta-analysis of individual participant data from randomised trials. Lancet 2009;373:1849-60.
2Xu J, Hahn JY, Song YB, Choi SH, Choi JH, Lu C, et al. Carina shift versus plaque shift for aggravation of side branch ostial stenosis in bifurcation lesions: Volumetric intravascular ultrasound analysis of both branches. Circ Cardiovasc Interv 2012;5:657-62.