|Year : 2018 | Volume
| Issue : 4 | Page : 111-112
Preface to fourth issue of Heart India 2018
Alok Kumar Singh
Department of Cardiology, Opal Hospital, Varanasi, Uttar Pradesh, India
|Date of Web Publication||17-Dec-2018|
Dr. Alok Kumar Singh
Department of Cardiology, Opal Hospital, Varanasi, Uttar Pradesh
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Singh AK. Preface to fourth issue of Heart India 2018. Heart India 2018;6:111-2
In this issue of “Heart India,” we are publishing one editorial, five original research articles, and four case reports. The success of interventional cardiology practice lies in its ability to reduce the severity of disease and to extend and improve the quality of life in patients with coronary artery disease. The novel BioMime Morph long-tapered sirolimus-eluting stent is designed to treat de novo long lesions in native coronary arteries with tapered anatomy. In the first article, Suresh has elegantly described the role of BioMime Morph stent in the treatment of coronary artery stenosis with tapered anatomy.
Abnormalities in the 12-lead electrocardiography (ECG) are often used to localize the anatomic site of myocardial infarction and ischemia in patients with coronary artery disease. In the first original research article, Gaude et al. have studied the coronary angiographic correlation with ECG in patients of acute coronary syndrome (ACS) ST-elevation myocardial infarction. In the second original research article, Gargi et al. have studied the role of mean platelet volume (MPV) in ACS. The authors of this study have concluded that the patients presenting with features of ACS have a higher MPV and a decreased platelet count as compared to normal population. In the third original research article, Richa et al. have studied the role of baseline hemoglobin (Hb) and creatinine clearance (CrCl) as a predictor of 30-day event rate in patients of acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention (PCI). The authors of this study have concluded that, in patients of acute STEMI undergoing primary PCI, both baseline-impaired CrCl and low Hb behaved independently as risk factors for increased 30-day event rates.
Coronary artery anomalies (CCAs) are rare congenital disorders with variable clinical presentation and incidence.
Most of the CCAs are clinically benign, and the majority are diagnosed incidentally during coronary angiography or an autopsy. In the fourth original research article, Nawale et al. have studied the clinical profile, incidence, pattern, and atherosclerotic involvement of congenital CCAs in adults undergoing coronary angiography.
Of 4481 angiograms screened, 86 patients were found to have CCA with the incidence of 1.91%. Nearly 76.7% of patients were male and 23.3% were female, with a mean age of 53.02 ± 10 years. Anomalies of origin and course were most common (94.18%), followed by anomalies of termination (5.81%), with right coronary artery (RCA) being the most common artery. Anomalous origin of RCA from the left sinus of Valsalva and separate origin of the left anterior descending artery and left circumflex artery were both found to be the most common types. The incidence of atherosclerosis in anomalous vessels was 52.32%.
Primary PCI is a recommended treatment of choice for ST-segment elevation myocardial infarction (STEMI) patients. In the fifth original research article, Akhil et al. have studied comparative outcomes of adjunctive and delayed routine pharmacoinvasive PCI strategy after thrombolysis in patients with ST-elevation myocardial infarction. The authors of this study have concluded that, even after 24 h of thrombolytic treatment in STEMI patients, delayed routine PCI can be performed with comparable outcome to that of PCI within 24 h.
In the first case report, Kola et al. have reported a case of myxoma presenting as rolling ball-like mass in the right atrium of a 6-year-old child. Pacemaker lead fracture is an uncommon cause of pacemaker failure. The incidence of lead fractures in pacemakers is about 1%–4%., In the second case report, Gupta et al. have reported a case of pacemaker lead fracture as a cause of pacing failure.
Familial hypercholesterolemia (FH) is a form of genetic dyslipidemia characterized by high levels of serum low-density lipoprotein cholesterol, tendon xanthomas, and family history of heart disease or elevated cholesterol. In the third case report, Nawale et al. have reported a case of a 24-year-old young male who presented with ACS, multiple skin and tendon xanthomas, family history of premature cardiac death, and diagnosed as FH with coronary artery disease which was treated with PCI and lipid-lowering therapy. In the fourth case report, Bhandari et al. have reported a case of sudden-onset painless unilateral vision loss postintravenous streptokinase in a patient of acute inferior-wall myocardial infarction.
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